Germline Stem Cells

Germ cells are specialized cells which are involved in reproduction. The most well-known examples of this type of cell are gametes, the sperm and eggs which come together to create a zygote which can develop into a foetus. In addition to gametes, a number of other cells involved in reproduction are also germ cells, including gonocytes, the cells which regulate the production of eggs and sperm. All germ cells carry the germ line, the genetic material which an organism can pass on to its offspring. In humans, these cells are haploid, meaning that they carry only half the number of chromosomes necessary to create an organism. When germ cells from two different people meet, their haploid genetic material combines to create diploid cells which can replicate themselves through cell division, ultimately building a baby.
  • Biologic and molecular basis of regenerative medicine
  • Fundamental molecular and genetic errors of disease
  • Cell- cell interactions
  • Germline stem cell populations maintained by instructions from a local niche
  • Invivo and Invitro Stem cell Microenvironment
  • Vertebrate Adult Stem cell Niche
  • Extracellular Matrix Mimicking strategies for Stem cell Niche
  • Cancer Stem Cell Niche

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