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Dr. M. James You completed his Ph.D from The University of Texas at Austin – 1997 and M.D. from Zhejiang University School of Medicine – 1986 and currently he is working as Associate Professor in Department of Hematopathology , The University of Texas MD Anderson Cancer Center, Houston, USA.
Our laboratory is interested in cancer biology and genetics as well as translational research. Our current focus is myeloid and lymphoid neoplasm using genetic and oncogenomic approaches to uncover important genetic events that may drive tumor initiation and progression. Approaches include Cre / Lox- and Flp / FRT-based conditional systems to generate genetically engineered mouse models, including acute leukemia, which permits studies of the underlying biology and mechanisms of various tumor types. In addition, we complement basic mechanistic studies with translational research on human tumor specimens, which helps to correlate genetic changes, expression profiling, or other molecular signatures with clinical behavior and outcome.